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Design Of Drug-Like Protein-Protein Interaction Stabilizers Guided By Chelation-Controlled Bioactive Conformation Stabil...

Project: TASPPI

Updated at: 28-04-2024

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Businessplan Startup

Project: TASPPI

Updated at: 28-04-2024

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Project acronym TASPPI

Periodic Reporting for period 2 - TASPPI (Targeted small-molecule Stabilisation of Protein-Protein Interactions)

Project: TASPPI

Updated at: 28-04-2024

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Project acronym TASPPI

Open Access Publication(s)

Project: TASPPI

Updated at: 28-04-2024

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Biophysical and structural insight into the USP8/14-3-3 interaction

Project: TASPPI

Updated at: 28-04-2024

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Project acronym TASPPI

Career Development Plan

Project: TASPPI

Updated at: 28-04-2024

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Project acronym TASPPI

Recruitment

Project: TASPPI

Updated at: 28-04-2024

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Project acronym TASPPI

Inhibition of 14-3-3/Tau by Hybrid Small-Molecule Peptides Operating via Two Different Binding Modes

Project: TASPPI

Updated at: 28-04-2024

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Project acronym TASPPI

Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein–Protein Interaction

Project: TASPPI

Updated at: 28-04-2024

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Project acronym TASPPI

Adoption of a Turn Conformation Drives the Binding Affinity of p53 C-Terminal Domain Peptides to 14-3-3σ

Project: TASPPI

Updated at: 28-04-2024

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Project acronym TASPPI

Clinical candidates modulating protein-protein interactions: The fragment-based experience

Project: TASPPI

Updated at: 28-04-2024

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Project acronym TASPPI

AMPK and AKT protein kinases hierarchically phosphorylate the N-terminus of the FOXO1 transcription factor, modulating i...

Project: TASPPI

Updated at: 28-04-2024

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Project acronym TASPPI

14-3-3 protein directly interacts with the kinase domain of calcium/calmodulin-dependent protein kinase kinase (CaMKK2)

Project: TASPPI

Updated at: 28-04-2024

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Project acronym TASPPI

Set-up and screening of a fragment library targeting the 14-3-3 protein interface

Project: TASPPI

Updated at: 28-04-2024

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Project acronym TASPPI

Nuclear Magnetic Resonance Spectroscopy Insights into Tau Structure in Solution: Impact of Post-translational Modificati...

Project: TASPPI

Updated at: 28-04-2024

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Project acronym TASPPI

Allosteric activation of yeast enzyme neutral trehalase by calcium and 14-3-3 protein

Project: TASPPI

Updated at: 28-04-2024

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Project acronym TASPPI

Structural characterization of 14-3-3ζ in complex with the human Son of sevenless homolog 1 (SOS1)

Project: TASPPI

Updated at: 28-04-2024

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Project acronym TASPPI

Backbone chemical shift assignments of human 14-3-3σ

Project: TASPPI

Updated at: 28-04-2024

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Project acronym TASPPI

Interaction of an IκBα Peptide with 14-3-3

Project: TASPPI

Updated at: 28-04-2024

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Project acronym TASPPI

Protein X-ray crystallography of the 14-3-3ζ/SOS1 complex

Project: TASPPI

Updated at: 28-04-2024

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Project acronym TASPPI

14-3-3: A Case Study in PPI Modulation

Project: TASPPI

Updated at: 28-04-2024

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Project acronym TASPPI

Researcher Declaration

Project: TASPPI

Updated at: 28-04-2024

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Project acronym TASPPI

Resources

Selected filters:

Design Of Drug-Like Protein-Protein Interaction Stabilizers Guided By Chelation-Controlled Bioactive Conformation Stabil...

Businessplan Startup

Periodic Reporting for period 2 - TASPPI (Targeted small-molecule Stabilisation of Protein-Protein Interactions)

Open Access Publication(s)

Biophysical and structural insight into the USP8/14-3-3 interaction

Career Development Plan

Recruitment

Inhibition of 14-3-3/Tau by Hybrid Small-Molecule Peptides Operating via Two Different Binding Modes

Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein–Protein Interaction

Adoption of a Turn Conformation Drives the Binding Affinity of p53 C-Terminal Domain Peptides to 14-3-3σ

Clinical candidates modulating protein-protein interactions: The fragment-based experience

AMPK and AKT protein kinases hierarchically phosphorylate the N-terminus of the FOXO1 transcription factor, modulating i...

14-3-3 protein directly interacts with the kinase domain of calcium/calmodulin-dependent protein kinase kinase (CaMKK2)

Set-up and screening of a fragment library targeting the 14-3-3 protein interface

Nuclear Magnetic Resonance Spectroscopy Insights into Tau Structure in Solution: Impact of Post-translational Modificati...

Allosteric activation of yeast enzyme neutral trehalase by calcium and 14-3-3 protein

Structural characterization of 14-3-3ζ in complex with the human Son of sevenless homolog 1 (SOS1)

Backbone chemical shift assignments of human 14-3-3σ

Interaction of an IκBα Peptide with 14-3-3

Protein X-ray crystallography of the 14-3-3ζ/SOS1 complex

14-3-3: A Case Study in PPI Modulation

Researcher Declaration