ERD

Selective Ring‐Opening of Di‐Substituted Epoxides Catalysed by Halohydrin Dehalogenases

Project: CARBAZYMES

Updated at: 29-04-2024

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2‐Deoxyribose‐5‐phosphate aldolase from Thermotoga maritima in the synthesis of a statin side‐chain precursor: c...

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Combining Aldolases and Transaminases for the Synthesis of 2-Amino-4-hydroxybutanoic Acid

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Alteration of the Route to Menaquinone towards Isochorismate‐Derived Metabolites

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Complete Switch of Reaction Specificity of an Aldolase by Directed Evolution In Vitro: Synthesis of Generic Aliphatic Al...

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Nucleophile Promiscuity of Engineered Class II Pyruvate Aldolase YfaU from E. Coli

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Enantioselective Synthesis of Pharmaceutically Active γ-Aminobutyric Acids Using a Tailor-Made Artificial Michaelase in...

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Structural and Mutagenesis Studies of the Thiamine-Dependent, Ketone-Accepting YerE from Pseudomonas protegens

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Updated at: 29-04-2024

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Aldolase-Catalyzed Asymmetric Synthesis of N-Heterocycles by Addition of Simple Aliphatic Nucleophiles to Aminoaldehydes

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Application of Chemical Engineering Methodology in Process Development: A Case Study of MenD-catalyzed Synthesis of 6-Cy...

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Biocatalytic Asymmetric Michael Additions of Nitromethane to α,β-Unsaturated Aldehydes via Enzyme-bound Iminium Ion In...

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nanoDSF as screening tool for enzyme libraries and biotechnology development

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Are in vivo selections on the path to extinction?

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Dissemination and branding standards

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International Outreach Symposium

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Fourth set of scientific publications

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Publicity materials

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Third set of scientific publications

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First set of scientific publications

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Posts, press releases, news items

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Cover Picture: Nucleophile Promiscuity of Engineered Class II Pyruvate Aldolase YfaU from E. Coli (Angew. Chem. Int....

Project: CARBAZYMES

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Second set of scientific publications

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Exploiting distant homologues for phasing through the generation of compact fragments, local fold refinement and partial...

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Biocatalytic Aldol Addition of Simple Aliphatic Nucleophiles to Hydroxyaldehydes

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Fluorogenic kinetic assay for high-throughput discovery of stereoselective ketoreductases relevant to pharmaceutical syn...

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2-Keto-3-Deoxy- l -Rhamnonate Aldolase (YfaU) as Catalyst in Aldol Additions of Pyruvate to Amino Aldehyde Derivatives

Project: CARBAZYMES

Updated at: 29-04-2024

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Mathematical model of the MenD-catalyzed 1,4-addition (Stetter reaction) of α-ketoglutaric acid to acrylonitrile

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Recent advances on halohydrin dehalogenases—from enzyme identification to novel biocatalytic applications

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The Generation and Exploitation of Protein Mutability Landscapes for Enzyme Engineering

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Project website

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