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Nucleophile Promiscuity of Engineered Class II Pyruvate Aldolase YfaU from E. Coli

Project: CARBAZYMES

Updated at: 29-04-2024

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Project acronym CARBAZYMES

Application of Chemical Engineering Methodology in Process Development: A Case Study of MenD-catalyzed Synthesis of 6-Cy...

Project: CARBAZYMES

Updated at: 29-04-2024

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Project acronym CARBAZYMES

nanoDSF as screening tool for enzyme libraries and biotechnology development

Project: CARBAZYMES

Updated at: 29-04-2024

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Project acronym CARBAZYMES

Aldolase-Catalyzed Asymmetric Synthesis of N-Heterocycles by Addition of Simple Aliphatic Nucleophiles to Aminoaldehydes

Project: CARBAZYMES

Updated at: 29-04-2024

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Project acronym CARBAZYMES

Complete Switch of Reaction Specificity of an Aldolase by Directed Evolution In Vitro: Synthesis of Generic Aliphatic Al...

Project: CARBAZYMES

Updated at: 29-04-2024

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Project acronym CARBAZYMES

Enantioselective Synthesis of Pharmaceutically Active γ-Aminobutyric Acids Using a Tailor-Made Artificial Michaelase in...

Project: CARBAZYMES

Updated at: 29-04-2024

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Project acronym CARBAZYMES

2‐Deoxyribose‐5‐phosphate aldolase from Thermotoga maritima in the synthesis of a statin side‐chain precursor: c...

Project: CARBAZYMES

Updated at: 29-04-2024

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Project acronym CARBAZYMES

Structural and Mutagenesis Studies of the Thiamine-Dependent, Ketone-Accepting YerE from Pseudomonas protegens

Project: CARBAZYMES

Updated at: 29-04-2024

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Project acronym CARBAZYMES

Biocatalytic Asymmetric Michael Additions of Nitromethane to α,β-Unsaturated Aldehydes via Enzyme-bound Iminium Ion In...

Project: CARBAZYMES

Updated at: 29-04-2024

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Project acronym CARBAZYMES

Selective Ring‐Opening of Di‐Substituted Epoxides Catalysed by Halohydrin Dehalogenases

Project: CARBAZYMES

Updated at: 29-04-2024

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Project acronym CARBAZYMES

Combining Aldolases and Transaminases for the Synthesis of 2-Amino-4-hydroxybutanoic Acid

Project: CARBAZYMES

Updated at: 29-04-2024

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Project acronym CARBAZYMES

Are in vivo selections on the path to extinction?

Project: CARBAZYMES

Updated at: 29-04-2024

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Project acronym CARBAZYMES

Alteration of the Route to Menaquinone towards Isochorismate‐Derived Metabolites

Project: CARBAZYMES

Updated at: 29-04-2024

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Project acronym CARBAZYMES

Dissemination and branding standards

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Updated at: 29-04-2024

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Project acronym CARBAZYMES

Exploiting distant homologues for phasing through the generation of compact fragments, local fold refinement and partial...

Project: CARBAZYMES

Updated at: 29-04-2024

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Project acronym CARBAZYMES

Biocatalytic Aldol Addition of Simple Aliphatic Nucleophiles to Hydroxyaldehydes

Project: CARBAZYMES

Updated at: 29-04-2024

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Project acronym CARBAZYMES

Recent advances on halohydrin dehalogenases—from enzyme identification to novel biocatalytic applications

Project: CARBAZYMES

Updated at: 29-04-2024

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Project acronym CARBAZYMES

The Generation and Exploitation of Protein Mutability Landscapes for Enzyme Engineering

Project: CARBAZYMES

Updated at: 29-04-2024

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Project acronym CARBAZYMES

Third set of scientific publications

Project: CARBAZYMES

Updated at: 29-04-2024

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2-Keto-3-Deoxy- l -Rhamnonate Aldolase (YfaU) as Catalyst in Aldol Additions of Pyruvate to Amino Aldehyde Derivatives

Project: CARBAZYMES

Updated at: 29-04-2024

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Project acronym CARBAZYMES

Mathematical model of the MenD-catalyzed 1,4-addition (Stetter reaction) of α-ketoglutaric acid to acrylonitrile

Project: CARBAZYMES

Updated at: 29-04-2024

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Project acronym CARBAZYMES

Posts, press releases, news items

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Cover Picture: Nucleophile Promiscuity of Engineered Class II Pyruvate Aldolase YfaU from E. Coli (Angew. Chem. Int....

Project: CARBAZYMES

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Fluorogenic kinetic assay for high-throughput discovery of stereoselective ketoreductases relevant to pharmaceutical syn...

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Fourth set of scientific publications

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International Outreach Symposium

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Updated at: 29-04-2024

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Second set of scientific publications

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Updated at: 29-04-2024

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First set of scientific publications

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Updated at: 29-04-2024

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Nucleophile Promiscuity of Engineered Class II Pyruvate Aldolase YfaU from E. Coli

Application of Chemical Engineering Methodology in Process Development: A Case Study of MenD-catalyzed Synthesis of 6-Cy...

nanoDSF as screening tool for enzyme libraries and biotechnology development

Aldolase-Catalyzed Asymmetric Synthesis of N-Heterocycles by Addition of Simple Aliphatic Nucleophiles to Aminoaldehydes

Complete Switch of Reaction Specificity of an Aldolase by Directed Evolution In Vitro: Synthesis of Generic Aliphatic Al...

Enantioselective Synthesis of Pharmaceutically Active γ-Aminobutyric Acids Using a Tailor-Made Artificial Michaelase in...

2‐Deoxyribose‐5‐phosphate aldolase from Thermotoga maritima in the synthesis of a statin side‐chain precursor: c...

Structural and Mutagenesis Studies of the Thiamine-Dependent, Ketone-Accepting YerE from Pseudomonas protegens

Biocatalytic Asymmetric Michael Additions of Nitromethane to α,β-Unsaturated Aldehydes via Enzyme-bound Iminium Ion In...

Selective Ring‐Opening of Di‐Substituted Epoxides Catalysed by Halohydrin Dehalogenases

Combining Aldolases and Transaminases for the Synthesis of 2-Amino-4-hydroxybutanoic Acid

Are in vivo selections on the path to extinction?

Alteration of the Route to Menaquinone towards Isochorismate‐Derived Metabolites

Dissemination and branding standards

Exploiting distant homologues for phasing through the generation of compact fragments, local fold refinement and partial...

Biocatalytic Aldol Addition of Simple Aliphatic Nucleophiles to Hydroxyaldehydes

Recent advances on halohydrin dehalogenases—from enzyme identification to novel biocatalytic applications

The Generation and Exploitation of Protein Mutability Landscapes for Enzyme Engineering

Third set of scientific publications

2-Keto-3-Deoxy- l -Rhamnonate Aldolase (YfaU) as Catalyst in Aldol Additions of Pyruvate to Amino Aldehyde Derivatives

Mathematical model of the MenD-catalyzed 1,4-addition (Stetter reaction) of α-ketoglutaric acid to acrylonitrile

Posts, press releases, news items

Publicity materials

Cover Picture: Nucleophile Promiscuity of Engineered Class II Pyruvate Aldolase YfaU from E. Coli (Angew. Chem. Int....

Fluorogenic kinetic assay for high-throughput discovery of stereoselective ketoreductases relevant to pharmaceutical syn...

Fourth set of scientific publications

Project website

International Outreach Symposium

Second set of scientific publications

First set of scientific publications