RADICALZ | RAPID DISCOVERY AND DEVELOPMENT OF ENZYMES FOR NOVEL AND GREENER CONSUMER PRODUCTS

Summary
The application of enzymes in industrial processes is increasingly important to achieve the EU’s sustainability goals and strengthen the bioeconomy, replacing oil-based chemistry. However, enzymes still find hurdles for their industrial application: low success rates of discovery and engineering; tedious and expensive methods to explore diversity; and limited activity/stability in the final application. RADICALZ assembles an interdisciplinary and intersectoral consortium to deliver faster, more versatile and more affordable tools for enzyme discovery and engineering, enabling the development of novel enzymes, new formulations and ingredients for more environment-friendly and healthier consumer products. This project will: i) develop new droplet microfluidic tools to find suitable enzymes for consumer products; ii) develop user-friendly software solutions based on machine learning (ML) for faster and more accurate enzyme engineering; iii) develop novel enzymes and bio-based, bio-catalytically synthesized ingredients for consumer products (glycosides, wash-enhancing enzymes, bio-based thickeners, natural antioxidants and fragrances); iv) develop bio-based, condition-responsive capsules for the protection and triggered release of enzymes and ingredients in the formulation of consumer products. RADICALZ will reduce the average time for enzyme discovery and evolution to
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/101000560
Start date: 01-06-2021
End date: 31-05-2025
Total budget - Public funding: 6 004 308,00 Euro - 6 004 308,00 Euro
Cordis data

Original description

The application of enzymes in industrial processes is increasingly important to achieve the EU’s sustainability goals and strengthen the bioeconomy, replacing oil-based chemistry. However, enzymes still find hurdles for their industrial application: low success rates of discovery and engineering; tedious and expensive methods to explore diversity; and limited activity/stability in the final application. RADICALZ assembles an interdisciplinary and intersectoral consortium to deliver faster, more versatile and more affordable tools for enzyme discovery and engineering, enabling the development of novel enzymes, new formulations and ingredients for more environment-friendly and healthier consumer products. This project will: i) develop new droplet microfluidic tools to find suitable enzymes for consumer products; ii) develop user-friendly software solutions based on machine learning (ML) for faster and more accurate enzyme engineering; iii) develop novel enzymes and bio-based, bio-catalytically synthesized ingredients for consumer products (glycosides, wash-enhancing enzymes, bio-based thickeners, natural antioxidants and fragrances); iv) develop bio-based, condition-responsive capsules for the protection and triggered release of enzymes and ingredients in the formulation of consumer products. RADICALZ will reduce the average time for enzyme discovery and evolution to

Status

SIGNED

Call topic

FNR-16-2020

Update Date

26-10-2022
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Horizon 2020
H2020-EU.3. SOCIETAL CHALLENGES
H2020-EU.3.2. SOCIETAL CHALLENGES - Food security, sustainable agriculture and forestry, marine, maritime and inland water research, and the bioeconomy
H2020-EU.3.2.0. Cross-cutting call topics
H2020-FNR-2020-2
FNR-16-2020 Enzymes for more environment-friendly consumer products