ERD

MultiSeq | Computational multiplexing to optimise next-generation sequencing

01-12-2023

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31-05-2025

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Organisation FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

PROSTarget | PROSTarget: Understanding the aggressive nature and key molecular drivers of metastatic dissemination in lethal PCa.

01-07-2023

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30-06-2025

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Organisation FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

STRUCTOMATIC | Mutational processes and impact of structural variants in somatic cells

01-02-2024

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31-01-2029

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Organisation FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

SENFIB | Novel senolytic drugs for the treatment of lung and kidney fibrosis

01-05-2021

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31-10-2022

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Organisation FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

CRC-MTOs | Colorectal Cancer Mouse Tumor Organoids as Pre-clinical Models for Therapeutical Testing

01-12-2018

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31-05-2020

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Organisation FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

2shRNA | 2shRNA branched nanobinders as promising therapeutic tools for combined cancer therapy

01-01-2019

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31-12-2020

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Organisation FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

CONCERT | Description of information transfer across macromolecules by concerted conformational changes

01-07-2015

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30-06-2021

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Organisation FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

HYPER-INSIGHT | Hypermutated tumors: insight into genome maintenance and cancer vulnerabilities provided by an extreme burden of somatic mutations

01-02-2018

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31-01-2024

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Organisation FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

p38_InTh | Innovative therapeutic tools to ameliorate chemotherapy-induced cardiotoxicity

01-12-2018

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31-08-2020

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Organisation FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

NONCODRIVERS | Finding noncoding cancer drivers

01-12-2016

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31-08-2023

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Organisation FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

LIPOMET | Dietary Influences on Metastasis: How, When, and Why

01-08-2018

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31-03-2024

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Organisation FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

MemOriStem | Origins and Consequences of Hematopoietic Stem Cell Memories

01-07-2022

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30-06-2027

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Organisation FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

TrickE3 | Chemical rewiring of E3 ubiquitin ligases as a generalizable therapeutic approach

01-03-2022

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28-02-2027

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Organisation FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

MitoSen | Detection and elimination of senescent cells targeting Cyclophilin D

01-09-2022

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31-08-2024

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Organisation FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

EpiHTStem | Understanding the Maintenance and Heritability of Hematopoietic Stem Cell Memories: High-Throughput Drug Screening Meets Single-Cell Barcoding

01-04-2023

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31-03-2025

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Organisation FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

MITOTUA | Connecting mitochondrial defects to reduced autophagy in metabolic liver diseases through FATP2.

01-09-2024

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31-08-2026

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Organisation FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

PalmitoMet | Targeting Palmitic Acid Signaling Machinery to Inhibit Metastatic Cancer

01-12-2023

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31-05-2025

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Organisation FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

MyTissue | Studying the metabolism and function of myeloid dendritic cells and neutrophils in distinct tissues in health and aging

01-01-2024

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31-12-2028

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Organisation FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

residualCRC | MECHANISMS BEHIND RESIDUAL DISEASE IN COLORECTAL CANCER and MODELLING OF THERAPIES THAT PREVENT RELAPSE

01-09-2020

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31-08-2025

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Organisation FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

p38Cure | New breast cancer therapies based on available p38 MAPK inhibitors

01-10-2015

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31-03-2017

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Organisation FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

COLOStage | COLOStage : A new prognosis test for the prediction of metastasis in Colorectal Cancer and Hepatocellular Carcinoma

01-03-2015

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31-08-2016

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Organisation FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

FRAGMENTOME | FRAGMENT screening from advanced-sampling molecular dynamics simulations on a proteOME scale.

01-05-2017

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04-06-2019

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Organisation FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

EPIDNA | Structural investigation of interplay between epigenetics, transcriptional regulation and DNA damage

01-04-2020

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31-03-2022

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Organisation FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

DesProtDNA | Computational design of proteins binding nucleosomal DNA with specificity for therapeutic applications

01-04-2017

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28-04-2019

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Organisation FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

GTR | Dissecting gamma-TuRC composition and activity by Single Molecule Pull-down

01-09-2017

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31-08-2019

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Organisation FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

IRB_DREAM | IRB DoctoRal fEllowship ProgrAMme: attracting international talent (IRB_DREAM)

01-09-2021

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31-08-2026

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Organisation FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

IRONAGE | Iron as a driver of fibrosis and regeneration

01-04-2018

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26-05-2020

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Organisation FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

Novel GIST Therapies | Targeted Protein Degradation as a Therapeutic Strategy for the Treatment of Gastrointestinal Stromal Tumour (GIST)

01-03-2025

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28-02-2027

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Organisation FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

Projects overview

Selected filters:

MultiSeq | Computational multiplexing to optimise next-generation sequencing

PROSTarget | PROSTarget: Understanding the aggressive nature and key molecular drivers of metastatic dissemination in lethal PCa.

STRUCTOMATIC | Mutational processes and impact of structural variants in somatic cells

SENFIB | Novel senolytic drugs for the treatment of lung and kidney fibrosis

CRC-MTOs | Colorectal Cancer Mouse Tumor Organoids as Pre-clinical Models for Therapeutical Testing

2shRNA | 2shRNA branched nanobinders as promising therapeutic tools for combined cancer therapy

CONCERT | Description of information transfer across macromolecules by concerted conformational changes

HYPER-INSIGHT | Hypermutated tumors: insight into genome maintenance and cancer vulnerabilities provided by an extreme burden of somatic mutations

p38_InTh | Innovative therapeutic tools to ameliorate chemotherapy-induced cardiotoxicity

NONCODRIVERS | Finding noncoding cancer drivers

LIPOMET | Dietary Influences on Metastasis: How, When, and Why

MemOriStem | Origins and Consequences of Hematopoietic Stem Cell Memories

TrickE3 | Chemical rewiring of E3 ubiquitin ligases as a generalizable therapeutic approach

MitoSen | Detection and elimination of senescent cells targeting Cyclophilin D

EpiHTStem | Understanding the Maintenance and Heritability of Hematopoietic Stem Cell Memories: High-Throughput Drug Screening Meets Single-Cell Barcoding

MITOTUA | Connecting mitochondrial defects to reduced autophagy in metabolic liver diseases through FATP2.

PalmitoMet | Targeting Palmitic Acid Signaling Machinery to Inhibit Metastatic Cancer

MyTissue | Studying the metabolism and function of myeloid dendritic cells and neutrophils in distinct tissues in health and aging

residualCRC | MECHANISMS BEHIND RESIDUAL DISEASE IN COLORECTAL CANCER and MODELLING OF THERAPIES THAT PREVENT RELAPSE

p38Cure | New breast cancer therapies based on available p38 MAPK inhibitors

COLOStage | COLOStage : A new prognosis test for the prediction of metastasis in Colorectal Cancer and Hepatocellular Carcinoma

FRAGMENTOME | FRAGMENT screening from advanced-sampling molecular dynamics simulations on a proteOME scale.

EPIDNA | Structural investigation of interplay between epigenetics, transcriptional regulation and DNA damage

DesProtDNA | Computational design of proteins binding nucleosomal DNA with specificity for therapeutic applications

GTR | Dissecting gamma-TuRC composition and activity by Single Molecule Pull-down

IRB_DREAM | IRB DoctoRal fEllowship ProgrAMme: attracting international talent (IRB_DREAM)

IRONAGE | Iron as a driver of fibrosis and regeneration

Novel GIST Therapies | Targeted Protein Degradation as a Therapeutic Strategy for the Treatment of Gastrointestinal Stromal Tumour (GIST)