ERD

EvolutioNeuroCircuit | Cellular and genetic bases of neural circuits evolution

01-03-2019

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31-01-2026

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

CHROMOREP | Reconstitution of Chromosome Replication and Epigenetic Inheritance

01-11-2015

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30-04-2022

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

PROTEUS | Predicting Routes Of Tumour Evolution driven by Unstable genomes and Selection

01-06-2019

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30-11-2024

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

PancObese | Metabolic mechanisms underpinning obesity-driven pancreatic cancer

01-09-2021

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31-08-2026

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

CAN_ORGANISE | Understanding and controlling the spatial organisation of cancer

01-10-2021

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30-09-2026

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

miRNA in Immunity | Testing the role of miRNA-mediated non-cell autonomous gene regulation in type-2 immunity

01-08-2015

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31-07-2020

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

XChromosome | Functions of the X chromosome in the mammalian germ line

01-11-2015

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30-04-2022

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

PregnantBrain | Neural adaptations during pregnancy

01-12-2019

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31-05-2025

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

ATG9_SOLVES_IT | In vitro high resolution reconstitution of autophagosome nucleation and expansion catalyzed by ATG9

01-07-2018

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31-12-2024

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

MeChroRep | Mechanism of Chromatin Replication

01-05-2022

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30-04-2027

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

ChromatidCohesion | Establishment of Sister Chromatid Cohesion

01-10-2015

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31-03-2022

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

DCPOIESIS | Steady-state and demand-driven dendritic cell generation

01-09-2018

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28-02-2025

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

WHOLENICHE | Hold it or let it go: a niche decision on cancer growth

01-04-2017

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30-09-2023

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

LogNeuroDev | The molecular and cellular logic of vertebrate neural development

01-01-2018

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30-06-2023

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

RASImmune | Targeting RAS driven tumour immune evasion

01-08-2019

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31-07-2025

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

DynaMO_TB | Spatiotemporal regulation of localization and replication of M. tuberculosis in human macrophages

01-09-2018

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31-08-2024

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

CRYOREP | Chromosome Replication Visualised by Cryo-EM

01-03-2019

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31-08-2025

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

AGRICON | Ancient genomic reconstruction of convergent evolution to agriculture

01-11-2019

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31-10-2024

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

VestibVis | Visual and vestibular processing in secondary visual cortex

01-03-2017

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28-02-2019

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

RETROFIT | Pinpointing novel molecular and cellular functions generated by retroelement onco-exaptation

01-12-2021

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30-11-2026

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

Cryo-H-Rec | Cryo-EM Imaging of Histone Recycling at the Replication Fork

01-04-2019

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31-03-2021

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

Irrev Fork Arrest | Deciphering the mechanism of irreversible replication fork arrest

01-04-2020

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31-03-2022

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

MechHelicaseActiv8on | Unravelling the mechanism of eukaryotic helicase activation

01-09-2022

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31-08-2024

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

SIOMICS | SIngle-cell multi-OMICs approach to study intra-tumour heterogeneity of soft tissue Sarcomas

01-04-2017

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31-03-2019

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

DECODE | Allele-specific Deconvolution of Tumour DNA Methylation and Expression Data to Reveal Underlying Cell Populations

01-08-2016

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31-07-2018

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

HollidayTrack | Tracking the movement and dynamics of Holliday junctions

01-04-2020

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31-03-2022

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

TxImmuneOrganoids | Divide and conquer: using patient-derived tumour organoids to dissect intra-tumour immune heterogeneity of non-small cell lung cancer

01-08-2021

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31-07-2023

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

SizerSingleCell | Molecular dynamics of size sensing at the single cell level.

01-09-2022

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31-08-2024

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

TRACERxTME | Constructing an evolutionary atlas of the immune landscape in lung cancer

01-04-2019

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31-03-2021

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

GLoopID | Mechanisms underlying regulation and removal of G-quadruplex/R-loop transcription-replication conflicts

01-09-2021

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04-01-2024

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Organisation THE FRANCIS CRICK INSTITUTE LIMITED

Projects overview

Selected filters:

EvolutioNeuroCircuit | Cellular and genetic bases of neural circuits evolution

CHROMOREP | Reconstitution of Chromosome Replication and Epigenetic Inheritance

PROTEUS | Predicting Routes Of Tumour Evolution driven by Unstable genomes and Selection

PancObese | Metabolic mechanisms underpinning obesity-driven pancreatic cancer

CAN_ORGANISE | Understanding and controlling the spatial organisation of cancer

miRNA in Immunity | Testing the role of miRNA-mediated non-cell autonomous gene regulation in type-2 immunity

XChromosome | Functions of the X chromosome in the mammalian germ line

PregnantBrain | Neural adaptations during pregnancy

ATG9_SOLVES_IT | In vitro high resolution reconstitution of autophagosome nucleation and expansion catalyzed by ATG9

MeChroRep | Mechanism of Chromatin Replication

ChromatidCohesion | Establishment of Sister Chromatid Cohesion

DCPOIESIS | Steady-state and demand-driven dendritic cell generation

WHOLENICHE | Hold it or let it go: a niche decision on cancer growth

LogNeuroDev | The molecular and cellular logic of vertebrate neural development

RASImmune | Targeting RAS driven tumour immune evasion

DynaMO_TB | Spatiotemporal regulation of localization and replication of M. tuberculosis in human macrophages

CRYOREP | Chromosome Replication Visualised by Cryo-EM

AGRICON | Ancient genomic reconstruction of convergent evolution to agriculture

VestibVis | Visual and vestibular processing in secondary visual cortex

RETROFIT | Pinpointing novel molecular and cellular functions generated by retroelement onco-exaptation

Cryo-H-Rec | Cryo-EM Imaging of Histone Recycling at the Replication Fork

Irrev Fork Arrest | Deciphering the mechanism of irreversible replication fork arrest

MechHelicaseActiv8on | Unravelling the mechanism of eukaryotic helicase activation

SIOMICS | SIngle-cell multi-OMICs approach to study intra-tumour heterogeneity of soft tissue Sarcomas

DECODE | Allele-specific Deconvolution of Tumour DNA Methylation and Expression Data to Reveal Underlying Cell Populations

HollidayTrack | Tracking the movement and dynamics of Holliday junctions

TxImmuneOrganoids | Divide and conquer: using patient-derived tumour organoids to dissect intra-tumour immune heterogeneity of non-small cell lung cancer

SizerSingleCell | Molecular dynamics of size sensing at the single cell level.

TRACERxTME | Constructing an evolutionary atlas of the immune landscape in lung cancer

GLoopID | Mechanisms underlying regulation and removal of G-quadruplex/R-loop transcription-replication conflicts