ERD

IDEAL | Inhibitor of DUX4-IGH to Erase Acute lymphoblastic Leukaemia

01-02-2020

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31-01-2022

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Organisation OSPEDALE SAN RAFFAELE SRL

ComBATageing | Exploiting superlongevous model mammals to explore new links between protein and organelle homeostasis and lifespan extension

01-09-2021

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31-08-2023

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Organisation OSPEDALE SAN RAFFAELE SRL

SoMuKT | SOmatic MUtagenesis in Kidney Tubule is enhanced by specific metabolic pathways

01-09-2020

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26-09-2022

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Organisation OSPEDALE SAN RAFFAELE SRL

BRAINeSs | Short-chain fatty acids in brain neuroinflammation: modulators of immunity and neural stemness

01-06-2021

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31-05-2023

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Organisation OSPEDALE SAN RAFFAELE SRL

EASY | Epigenetic approach for the treatment of obesity

01-07-2017

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01-12-2019

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Organisation OSPEDALE SAN RAFFAELE SRL

Hepatocarcinoma IVM | Spatiotemporal dynamics of CD8+ T cell responses to hepatocellular carcinoma

01-07-2017

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30-06-2019

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Organisation OSPEDALE SAN RAFFAELE SRL

ASTRO-EDITING | Targeting ASTROcytes with cutting-edge EDITING technologies to treat the Alexander disease

01-07-2020

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30-06-2022

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Organisation OSPEDALE SAN RAFFAELE SRL

RTTOPHAGY | """Investigating autophagy enhancement as a therapeutic approach for the treatment of Rett syndrome."""

03-06-2019

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16-06-2021

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Organisation OSPEDALE SAN RAFFAELE SRL

DADA2GT | Development of gene therapy and genome editing strategies to treat adenosine deaminase 2 deficiency

01-06-2019

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31-05-2021

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Organisation OSPEDALE SAN RAFFAELE SRL

THAT IS HUNT | Triggering Haematological Adoptive T-cell Immunotherapy Strategies by HUnting Novel T-cell receptors

01-01-2018

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31-12-2019

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Organisation OSPEDALE SAN RAFFAELE SRL

IMPACT-HEALTH | IMaging Pancreatic Alpha-cells Calcium Tied with HEterogeneous Analysis of Labeled Transcription factors with in situ Hybridization

17-09-2018

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16-09-2020

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Organisation OSPEDALE SAN RAFFAELE SRL

CERVINO | Can human embryo-released extracellular vesicles govern endometrial receptivity and inform on vanguard embryo diagnostics and fertility therapeutics?

02-07-2018

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01-07-2020

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Organisation OSPEDALE SAN RAFFAELE SRL

DREAM | Dux4-Regulated Expression and Activity by an inhibitor Molecule

01-03-2021

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28-02-2023

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Organisation OSPEDALE SAN RAFFAELE SRL

IMPROVING-GT | Innovative strategies to increase engraftment of engineered hematopoietic stem cells and bypass genotoxic conditioning, toward the next-generation gene therapy

01-01-2022

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31-12-2023

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Organisation OSPEDALE SAN RAFFAELE SRL

LEUKEYOLK | Uncovering the origin and mechanisms of Down syndrome-associated leukaemia through human induced pluripotent stem cell-derived haemopoiesis

01-02-2019

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31-01-2021

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Organisation OSPEDALE SAN RAFFAELE SRL

IC_IL_EC_2017 | Investigating the effects of immunogenic chemoradiation in shaping the immune landscape of esophageal cancers

01-03-2018

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19-05-2020

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Organisation OSPEDALE SAN RAFFAELE SRL

MOD-REG | Modulating Tregs in liver disease for therapeutic benefit

01-05-2024

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30-04-2026

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Organisation OSPEDALE SAN RAFFAELE SRL

LAMA2-TFIMG | Tackling fibrosis and inflammation in LAMA2-RD by in vivo modulation of a novel modifier gene

01-01-2025

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31-12-2026

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Organisation OSPEDALE SAN RAFFAELE SRL

Projects overview

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IDEAL | Inhibitor of DUX4-IGH to Erase Acute lymphoblastic Leukaemia

ComBATageing | Exploiting superlongevous model mammals to explore new links between protein and organelle homeostasis and lifespan extension

SoMuKT | SOmatic MUtagenesis in Kidney Tubule is enhanced by specific metabolic pathways

BRAINeSs | Short-chain fatty acids in brain neuroinflammation: modulators of immunity and neural stemness

EASY | Epigenetic approach for the treatment of obesity

Hepatocarcinoma IVM | Spatiotemporal dynamics of CD8+ T cell responses to hepatocellular carcinoma

ASTRO-EDITING | Targeting ASTROcytes with cutting-edge EDITING technologies to treat the Alexander disease

RTTOPHAGY | """Investigating autophagy enhancement as a therapeutic approach for the treatment of Rett syndrome."""

DADA2GT | Development of gene therapy and genome editing strategies to treat adenosine deaminase 2 deficiency

THAT IS HUNT | Triggering Haematological Adoptive T-cell Immunotherapy Strategies by HUnting Novel T-cell receptors

IMPACT-HEALTH | IMaging Pancreatic Alpha-cells Calcium Tied with HEterogeneous Analysis of Labeled Transcription factors with in situ Hybridization

CERVINO | Can human embryo-released extracellular vesicles govern endometrial receptivity and inform on vanguard embryo diagnostics and fertility therapeutics?

DREAM | Dux4-Regulated Expression and Activity by an inhibitor Molecule

IMPROVING-GT | Innovative strategies to increase engraftment of engineered hematopoietic stem cells and bypass genotoxic conditioning, toward the next-generation gene therapy

LEUKEYOLK | Uncovering the origin and mechanisms of Down syndrome-associated leukaemia through human induced pluripotent stem cell-derived haemopoiesis

IC_IL_EC_2017 | Investigating the effects of immunogenic chemoradiation in shaping the immune landscape of esophageal cancers

MOD-REG | Modulating Tregs in liver disease for therapeutic benefit

LAMA2-TFIMG | Tackling fibrosis and inflammation in LAMA2-RD by in vivo modulation of a novel modifier gene