Database containing simulated whole-exome or whole-genome sequencing data from 5-10 individuals

We will generate simulated whole exome or whole genome sequencing data from 5-10 individuals, each with specific mutations and other variants that evoke challenging scenarios in the GCOF. We will introduce both known mutations (e.g. BRCA1) and hypothetical ones (e.g. a ‘happiness’ variant) in these data. The hypothetical variants are not necessarily expected to be identified in future genetic research; they rather reflect controversial topics that could be appearing from general health-related research, and that could evoke fundamental societal challenges. The data will be stored on a central server (Cartagenia, biologis) and made available for all stakeholders in the project in a controlled and condensed way.