ERD

Targeting serine hydroxymethyltransferases 1 and 2 for T-cell acute lymphoblastic leukemia therapy

Project: AltCheM

Updated at: 31-08-2024

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Project acronym AltCheM

P2RY2-AKT activation is a therapeutically actionable consequence of XPO1 inhibition in acute myeloid leukemia

Project: AltCheM

Updated at: 14-05-2024

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Project acronym AltCheM

Matched Targeted Therapy for Pediatric Patients with Relapsed, Refractory or High-risk Leukemias: A Report from the LEAP...

Project: AltCheM

Updated at: 14-05-2024

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Project acronym AltCheM

Cystine uptake inhibition potentiates front-line therapies in acute myeloid leukemia

Project: AltCheM

Updated at: 14-05-2024

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Project acronym AltCheM

The Folate Cycle Enzyme MTHFR Is a Critical Regulator of Cell Response to MYC-Targeting Therapies

Project: AltCheM

Updated at: 27-04-2024

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Project acronym AltCheM

HER2 Signaling Hijacks the Creatine Shuttle to Fuel Breast Cancer Cell Growth

Project: AltCheM

Updated at: 27-04-2024

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Project acronym AltCheM

Exploiting an Asp-Glu “switch” in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute...

Project: AltCheM

Updated at: 27-04-2024

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Project acronym AltCheM

Targeting acute myeloid leukemia dependency on VCP-mediated DNA repair through a selective second-generation small-molec...

Project: AltCheM

Updated at: 27-04-2024

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Project acronym AltCheM

Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer

Project: AltCheM

Updated at: 27-04-2024

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Project acronym AltCheM

CDK6 is an essential direct target of NUP98 fusion proteins in acute myeloid leukemia

Project: AltCheM

Updated at: 27-04-2024

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Project acronym AltCheM

Creatine kinase pathway inhibition alters GSK3 and WNT signaling in EVI1-positive AML

Project: AltCheM

Updated at: 27-04-2024

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Project acronym AltCheM

Periodic Reporting for period 3 - AltCheM (In vivo functional screens to decipher mechanisms of stochastically- and muta...

Project: AltCheM

Updated at: 27-04-2024

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Project acronym AltCheM

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Targeting serine hydroxymethyltransferases 1 and 2 for T-cell acute lymphoblastic leukemia therapy

P2RY2-AKT activation is a therapeutically actionable consequence of XPO1 inhibition in acute myeloid leukemia

Matched Targeted Therapy for Pediatric Patients with Relapsed, Refractory or High-risk Leukemias: A Report from the LEAP...

Cystine uptake inhibition potentiates front-line therapies in acute myeloid leukemia

The Folate Cycle Enzyme MTHFR Is a Critical Regulator of Cell Response to MYC-Targeting Therapies

HER2 Signaling Hijacks the Creatine Shuttle to Fuel Breast Cancer Cell Growth

Exploiting an Asp-Glu “switch” in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute...

Targeting acute myeloid leukemia dependency on VCP-mediated DNA repair through a selective second-generation small-molec...

Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer

CDK6 is an essential direct target of NUP98 fusion proteins in acute myeloid leukemia

Creatine kinase pathway inhibition alters GSK3 and WNT signaling in EVI1-positive AML

Periodic Reporting for period 3 - AltCheM (In vivo functional screens to decipher mechanisms of stochastically- and muta...