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Lentiviral transduction of mammalian cells for fast, scalable and high-level production of soluble and membrane proteins

Project: CilDyn

Updated at: 27-04-2024

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Project acronym CilDyn

Calcium-sensing receptor residues with loss- and gain-of-function mutations are located in regions of conformational cha...

Project: CilDyn

Updated at: 27-04-2024

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Project acronym CilDyn

Acylation-coupled lipophilic induction of polarisation (Acyl-cLIP): a universal assay for lipid transferase and hydrolas...

Project: CilDyn

Updated at: 27-04-2024

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Project acronym CilDyn

Structures of vertebrate Patched and Smoothened reveal intimate links between cholesterol and Hedgehog signalling

Project: CilDyn

Updated at: 27-04-2024

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Project acronym CilDyn

Cholesterol accessibility at the ciliary membrane controls hedgehog signaling

Project: CilDyn

Updated at: 27-04-2024

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Project acronym CilDyn

The morphogen Sonic hedgehog inhibits its receptor Patched by a pincer grasp mechanism

Project: CilDyn

Updated at: 27-04-2024

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Project acronym CilDyn

Diversity of oligomerization in Drosophila semaphorins suggests a mechanism of functional fine-tuning

Project: CilDyn

Updated at: 27-04-2024

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Project acronym CilDyn

Biochemical mechanisms of vertebrate hedgehog signaling

Project: CilDyn

Updated at: 27-04-2024

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Project acronym CilDyn

iASPP mediates p53 selectivity through a modular mechanism fine-tuning DNA recognition

Project: CilDyn

Updated at: 27-04-2024

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Project acronym CilDyn

Cholesterol Interaction Sites on the Transmembrane Domain of the Hedgehog Signal Transducer and Class F G Protein-Couple...

Project: CilDyn

Updated at: 27-04-2024

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Project acronym CilDyn

Repulsive guidance molecules lock growth differentiation factor 5 in an inhibitory complex

Project: CilDyn

Updated at: 27-04-2024

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Project acronym CilDyn

R-spondins engage heparan sulfate proteoglycans to potentiate WNT signaling

Project: CilDyn

Updated at: 27-04-2024

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Project acronym CilDyn

Structure and Mechanism of Hedgehog Acyl Transferase

Project: CilDyn

Updated at: 27-04-2024

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Project acronym CilDyn

Robin Hood: non-fitting, non-smoothing image detrending for bleaching correction

Project: CilDyn

Updated at: 27-04-2024

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Project acronym CilDyn

Cholesterol access in cellular membranes controls Hedgehog signaling

Project: CilDyn

Updated at: 27-04-2024

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Project acronym CilDyn

A calcium-sensing receptor mutation causing hypocalcemia disrupts a transmembrane salt bridge to activate β-arrestin–...

Project: CilDyn

Updated at: 27-04-2024

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Project acronym CilDyn

Structural basis of Smoothened regulation by its extracellular domains

Project: CilDyn

Updated at: 27-04-2024

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Project acronym CilDyn

Photochemical Probe Identification of a Small‐Molecule Inhibitor Binding Site in Hedgehog Acyltransferase (HHAT)**

Project: CilDyn

Updated at: 27-04-2024

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Project acronym CilDyn

Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling

Project: CilDyn

Updated at: 27-04-2024

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Project acronym CilDyn

Multiple ligand binding sites regulate the Hedgehog signal transducer Smoothened in vertebrates

Project: CilDyn

Updated at: 27-04-2024

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Project acronym CilDyn

RGMs: Structural Insights, Molecular Regulation, and Downstream Signaling

Project: CilDyn

Updated at: 27-04-2024

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Project acronym CilDyn

Cholesterol activates the G-protein coupled receptor Smoothened to promote Hedgehog signaling

Project: CilDyn

Updated at: 27-04-2024

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Project acronym CilDyn

Periodic Reporting for period 4 - CilDyn (Molecular analysis of the Hedgehog signal transduction complex in the primary ...

Project: CilDyn

Updated at: 27-04-2024

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Project acronym CilDyn

Calibration-free <em>In Vitro</em> Quantification of Protein Homo-oligomerization Using Commercial Instrumentation and F...

Project: CilDyn

Updated at: 27-04-2024

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Project acronym CilDyn

Cilia-Associated Oxysterols Activate Smoothened

Project: CilDyn

Updated at: 27-04-2024

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Project acronym CilDyn

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Lentiviral transduction of mammalian cells for fast, scalable and high-level production of soluble and membrane proteins

Calcium-sensing receptor residues with loss- and gain-of-function mutations are located in regions of conformational cha...

Acylation-coupled lipophilic induction of polarisation (Acyl-cLIP): a universal assay for lipid transferase and hydrolas...

Structures of vertebrate Patched and Smoothened reveal intimate links between cholesterol and Hedgehog signalling

Cholesterol accessibility at the ciliary membrane controls hedgehog signaling

The morphogen Sonic hedgehog inhibits its receptor Patched by a pincer grasp mechanism

Diversity of oligomerization in Drosophila semaphorins suggests a mechanism of functional fine-tuning

Biochemical mechanisms of vertebrate hedgehog signaling

iASPP mediates p53 selectivity through a modular mechanism fine-tuning DNA recognition

Cholesterol Interaction Sites on the Transmembrane Domain of the Hedgehog Signal Transducer and Class F G Protein-Couple...

Repulsive guidance molecules lock growth differentiation factor 5 in an inhibitory complex

R-spondins engage heparan sulfate proteoglycans to potentiate WNT signaling

Structure and Mechanism of Hedgehog Acyl Transferase

Robin Hood: non-fitting, non-smoothing image detrending for bleaching correction

Cholesterol access in cellular membranes controls Hedgehog signaling

A calcium-sensing receptor mutation causing hypocalcemia disrupts a transmembrane salt bridge to activate β-arrestin–...

Structural basis of Smoothened regulation by its extracellular domains

Photochemical Probe Identification of a Small‐Molecule Inhibitor Binding Site in Hedgehog Acyltransferase (HHAT)**

Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling

Multiple ligand binding sites regulate the Hedgehog signal transducer Smoothened in vertebrates

RGMs: Structural Insights, Molecular Regulation, and Downstream Signaling

Cholesterol activates the G-protein coupled receptor Smoothened to promote Hedgehog signaling

Periodic Reporting for period 4 - CilDyn (Molecular analysis of the Hedgehog signal transduction complex in the primary ...

Calibration-free <em>In Vitro</em> Quantification of Protein Homo-oligomerization Using Commercial Instrumentation and F...

Cilia-Associated Oxysterols Activate Smoothened