ERD

SafeFate | Safeguarding Cell Fate by Terminal Repression during Development and Disease

01-02-2019

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31-01-2025

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Organisation DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG

REBUILDCNS | Redirecting glial progenitor fate to rebuild the injured Brain

01-06-2018

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31-05-2023

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Organisation DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG

Cancer-Harakiri | Targeting the undruggable: Leveraging neomorphic DNA-binding preferences of chimeric fusion oncogenes to promote cancer suicide

01-01-2024

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31-12-2028

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Organisation DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG

SpatialTMEMetabolism | Spatial Quantification of Cellular Metabolism in the Tumor Immune Microenvironment

01-09-2023

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31-08-2028

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Organisation DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG

4D-therapy | Multimodal “4D”-therapy of pediatric high grade glioma

01-01-2024

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31-12-2028

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Organisation DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG

FAITH | Fatty liver Nano-/Antibody Therapy - (FAITH)

01-08-2020

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31-01-2022

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Organisation DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG

Redox Relays | Detecting, understanding and exploiting intracellular redox signaling relays

01-10-2017

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31-03-2024

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Organisation DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG

DualRP | Exploring cell interactions in the tumor microenvironment with dual ribosome profiling

01-06-2018

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31-05-2024

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Organisation DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG

PedSarc | Targeting genetic and epigenetic mechanisms in pediatric sarcomas.

01-01-2019

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31-12-2024

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Organisation DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG

BrainBreaks | DNA Breaks Shape Neural Genome Heterogeneity

01-01-2021

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31-12-2025

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Organisation DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG

CTCFStableGenome | CTCF control of genome stability in ageing

01-09-2019

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31-08-2024

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Organisation DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG

CancerHetero | Dissection of tumor heterogeneity in vivo

01-06-2015

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31-05-2020

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Organisation DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG

DIEAML | Deciphering immune evasion of Acute Myeloid Leukemia

01-09-2022

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01-12-2024

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Organisation DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG

SCEPTRE | Single Cell EPigenomic, Transcriptomic, and structural Rearrangement profiling to investigate Evolution in prostate cancer

10-04-2021

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09-04-2023

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Organisation DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG

Rn7SKmod | Impact of RNA modifications on neuronal fate

01-07-2021

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30-06-2023

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Organisation DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG

CENTR-ALL | Clarifying role of the CENTROSOME in abnormal mitotic processes featuring the most common childhood malignancy: paediatric High Hyperdiploid Acute Lymphoblastic Leukaemia (HHDpALL)

24-01-2019

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23-01-2021

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Organisation DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG

VulneraBAP1 | Mechanism and vulnerability of BAP1 loss in tumor metastasis

01-07-2018

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30-06-2020

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Organisation DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG

TWSCC | Trafficking of Wnt Signaling Components in Cancer

01-09-2021

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31-08-2023

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Organisation DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG

TimedEnhancer | Temporal dependence of enhancer function

01-06-2024

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31-05-2029

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Organisation DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG

VulnerableInhibition | Cognitive deficits resulting from selective vulnerability of septal inhibitory neurons: mitochondrial dysfunction as a driver?

01-09-2024

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31-08-2028

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Organisation DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG

METABAC | Functional characterization of the colorectal cancer metastasis microbiome

01-10-2024

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30-09-2029

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Organisation DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG

Projects overview

Selected filters:

SafeFate | Safeguarding Cell Fate by Terminal Repression during Development and Disease

REBUILDCNS | Redirecting glial progenitor fate to rebuild the injured Brain

Cancer-Harakiri | Targeting the undruggable: Leveraging neomorphic DNA-binding preferences of chimeric fusion oncogenes to promote cancer suicide

SpatialTMEMetabolism | Spatial Quantification of Cellular Metabolism in the Tumor Immune Microenvironment

4D-therapy | Multimodal “4D”-therapy of pediatric high grade glioma

FAITH | Fatty liver Nano-/Antibody Therapy - (FAITH)

Redox Relays | Detecting, understanding and exploiting intracellular redox signaling relays

DualRP | Exploring cell interactions in the tumor microenvironment with dual ribosome profiling

PedSarc | Targeting genetic and epigenetic mechanisms in pediatric sarcomas.

BrainBreaks | DNA Breaks Shape Neural Genome Heterogeneity

CTCFStableGenome | CTCF control of genome stability in ageing

CancerHetero | Dissection of tumor heterogeneity in vivo

DIEAML | Deciphering immune evasion of Acute Myeloid Leukemia

SCEPTRE | Single Cell EPigenomic, Transcriptomic, and structural Rearrangement profiling to investigate Evolution in prostate cancer

Rn7SKmod | Impact of RNA modifications on neuronal fate

CENTR-ALL | Clarifying role of the CENTROSOME in abnormal mitotic processes featuring the most common childhood malignancy: paediatric High Hyperdiploid Acute Lymphoblastic Leukaemia (HHDpALL)

VulneraBAP1 | Mechanism and vulnerability of BAP1 loss in tumor metastasis

TWSCC | Trafficking of Wnt Signaling Components in Cancer

TimedEnhancer | Temporal dependence of enhancer function

VulnerableInhibition | Cognitive deficits resulting from selective vulnerability of septal inhibitory neurons: mitochondrial dysfunction as a driver?

METABAC | Functional characterization of the colorectal cancer metastasis microbiome