ERD

In vivo models and endpoints

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

Oxaliplatin-Induced Neuropathy: Genetic and Epigenetic Profile to Better Understand How to Ameliorate This Side Effect

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

Pharmaceuticals reported to induce P/P adverse events

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

Data exchange SOPs, QA guidelines, and Data Management Plan

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

Data Mining Software

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

New improved in vitro tool for screening seizure-inducing liabilities, especially using stem cell systems

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

Neurofilament light chain in plasma as a sensitive diagnostic biomarker of peripheral neurotoxicity: In Vivo mouse studi...

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

Molecular Mingling: Multimodal Predictions of Ligand Promiscuity in Pentameric Ligand-Gated Ion Channels

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

A new set of KNIME nodes implementing the QPhAR algorithm

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

Multiscale integrative modeling and novel AE biology

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

Protocols for Toolbox Verification

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

Evaluation report of the toolbox performance

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

Final Report on Dissemination Activities and Use of Results

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

NeuroDeRisk Toolbox

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

VEGF-A/VEGFR-1 signalling and chemotherapy-induced neuropathic pain: therapeutic potential of a novel anti-VEGFR-1 monoc...

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

Submission of a scientific paper on the NeuroDeRisk project

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

Project Handbook

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

Molecular basis of mood and cognitive adverse events elucidated via a combination of pharmacovigilance data mining and f...

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

List of compounds for further testing

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

Periodic Reporting for period 3 - NeuroDeRisk (Neurotoxicity De-Risking in Preclinical Drug Discovery)

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

Select In vitro models of PNS-Tox

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

Contributive role of CNS barriers in achievement of extracellular and intracellular unbound compound exposure in brain r...

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

Inhibitors of Mitochondrial Human Carbonic Anhydrases VA and VB as a Therapeutic Strategy against Paclitaxel-Induced Neu...

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

Novel alpha6 preferring GABA-A receptor ligands based on loreclezole

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

Applications of the Novel Quantitative Pharmacophore Activity Relationship Method QPhAR in Virtual Screening and Lead-Op...

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

A Semi-Automatic Method for the Quantification of Astrocyte Number and Branching in Bulk Immunohistochemistry Images

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

Single and combinatory safety biomarkers for detection of risk for convulsive seizures

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

New improved in vivo animal models and tools, allowing focused non- invasive detection of seizure-inducing effects durin...

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

Neuropharmacophore modeling

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

QPHAR: quantitative pharmacophore activity relationship: method and validation

Project: NeuroDeRisk

Updated at: 29-04-2024

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Project acronym NeuroDeRisk

Resources

Selected filters:

In vivo models and endpoints

Oxaliplatin-Induced Neuropathy: Genetic and Epigenetic Profile to Better Understand How to Ameliorate This Side Effect

Pharmaceuticals reported to induce P/P adverse events

Data exchange SOPs, QA guidelines, and Data Management Plan

Data Mining Software

New improved in vitro tool for screening seizure-inducing liabilities, especially using stem cell systems

Neurofilament light chain in plasma as a sensitive diagnostic biomarker of peripheral neurotoxicity: In Vivo mouse studi...

Molecular Mingling: Multimodal Predictions of Ligand Promiscuity in Pentameric Ligand-Gated Ion Channels

A new set of KNIME nodes implementing the QPhAR algorithm

Multiscale integrative modeling and novel AE biology

Protocols for Toolbox Verification

Evaluation report of the toolbox performance

Final Report on Dissemination Activities and Use of Results

NeuroDeRisk Toolbox

VEGF-A/VEGFR-1 signalling and chemotherapy-induced neuropathic pain: therapeutic potential of a novel anti-VEGFR-1 monoc...

Submission of a scientific paper on the NeuroDeRisk project

Project Handbook

Molecular basis of mood and cognitive adverse events elucidated via a combination of pharmacovigilance data mining and f...

List of compounds for further testing

Periodic Reporting for period 3 - NeuroDeRisk (Neurotoxicity De-Risking in Preclinical Drug Discovery)

Select In vitro models of PNS-Tox

Contributive role of CNS barriers in achievement of extracellular and intracellular unbound compound exposure in brain r...

Inhibitors of Mitochondrial Human Carbonic Anhydrases VA and VB as a Therapeutic Strategy against Paclitaxel-Induced Neu...

Novel alpha6 preferring GABA-A receptor ligands based on loreclezole

Applications of the Novel Quantitative Pharmacophore Activity Relationship Method QPhAR in Virtual Screening and Lead-Op...

A Semi-Automatic Method for the Quantification of Astrocyte Number and Branching in Bulk Immunohistochemistry Images

Single and combinatory safety biomarkers for detection of risk for convulsive seizures

New improved in vivo animal models and tools, allowing focused non- invasive detection of seizure-inducing effects durin...

Neuropharmacophore modeling

QPHAR: quantitative pharmacophore activity relationship: method and validation