ERD

Rewiring of catecholamine-induced calcium signalling is an early event in non-alcoholic fatty liver disease

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

Bioengineered Pancreas–Liver Crosstalk in a Microfluidic Coculture Chip Identifies Human Metabolic Response Signatures...

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

200 protein structures in years 2 and 3

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

Data deposition of genome/proteome wide analysis for >60 CG compounds

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

Steady state sample access (1-2 per week) from IBD and CRC

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

10 recombinant antibodies or binders in year 1

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

100 targets enabled with in vitro assays and 60 targets with cellular assays in year 2 and 3

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

Image-Based Annotation of Chemogenomic Libraries for Phenotypic Screening

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

Data ontology defined by working group

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

Automated Determination of Nuclear Magnetic Resonance Chemical Shift Perturbations in Ligand Screening Experiments: The ...

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

Ten PCAs established and/or optimised (20 in total)

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

40 CP in year 2 and 3

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

600 proteins purified in year 2 and 3

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

Distribution of approved CG sets and CP

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

Agreed quality control criteria approved by JMC

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

Web-based internal database system initial implementation

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

LiP-MS or BioID datasets of ≥10 probe-cell interactions

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

Computational tools to assess the functional consequences of rare and noncoding pharmacogenetic variability

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

Pharmacogene Sequencing of a Gabonese Population with Severe Plasmodium falciparum Malaria Reveals Multiple Novel Varian...

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

Amide-to-ester substitution as a strategy for optimizing PROTAC permeability and cellular activity

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

Binding Adaptation of GS-441524Diversifies Macro Domains and Down-regulates SARS-CoV-2 de-MARylationCapacity

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

Open resources for chemical probes and their implications for future drug discovery

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

Chemical Starting Matter for HNF4α Ligand Discovery and Chemogenomics

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

Human MettL3-MettL14 RNA adenine methyltransferase complex is active on double-stranded DNA containing lesions.

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

Stopping pandemics before they start: Lessons learned from SARS-CoV-2

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

A pro-Fluorescent Ubiquitin-based Probe to Monitor Cysteine-based E3 Ligase Activity

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

Structural and functional characterization of ubiquitin variant inhibitors for the JAMM-family deubiquitinases STAMBP an...

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

PRMT5 regulates ATF4 transcript splicing and oxidative stress response.

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

Intermediate release of curated CG compound profiling data

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

First review of data ontology

Project: EUbOPEN

Updated at: 30-10-2023

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Project acronym EUbOPEN

Resources

Selected filters:

Rewiring of catecholamine-induced calcium signalling is an early event in non-alcoholic fatty liver disease

Bioengineered Pancreas–Liver Crosstalk in a Microfluidic Coculture Chip Identifies Human Metabolic Response Signatures...

200 protein structures in years 2 and 3

Data deposition of genome/proteome wide analysis for >60 CG compounds

Steady state sample access (1-2 per week) from IBD and CRC

10 recombinant antibodies or binders in year 1

100 targets enabled with in vitro assays and 60 targets with cellular assays in year 2 and 3

Image-Based Annotation of Chemogenomic Libraries for Phenotypic Screening

Data ontology defined by working group

Automated Determination of Nuclear Magnetic Resonance Chemical Shift Perturbations in Ligand Screening Experiments: The ...

Ten PCAs established and/or optimised (20 in total)

40 CP in year 2 and 3

600 proteins purified in year 2 and 3

Distribution of approved CG sets and CP

Agreed quality control criteria approved by JMC

Web-based internal database system initial implementation

LiP-MS or BioID datasets of ≥10 probe-cell interactions

Computational tools to assess the functional consequences of rare and noncoding pharmacogenetic variability

Pharmacogene Sequencing of a Gabonese Population with Severe Plasmodium falciparum Malaria Reveals Multiple Novel Varian...

Amide-to-ester substitution as a strategy for optimizing PROTAC permeability and cellular activity

Binding Adaptation of GS-441524Diversifies Macro Domains and Down-regulates SARS-CoV-2 de-MARylationCapacity

Open resources for chemical probes and their implications for future drug discovery

Chemical Starting Matter for HNF4α Ligand Discovery and Chemogenomics

Human MettL3-MettL14 RNA adenine methyltransferase complex is active on double-stranded DNA containing lesions.

Stopping pandemics before they start: Lessons learned from SARS-CoV-2

A pro-Fluorescent Ubiquitin-based Probe to Monitor Cysteine-based E3 Ligase Activity

Structural and functional characterization of ubiquitin variant inhibitors for the JAMM-family deubiquitinases STAMBP an...

PRMT5 regulates ATF4 transcript splicing and oxidative stress response.

Intermediate release of curated CG compound profiling data

First review of data ontology